Peptide Therapy FAQ's

Peptide Therapy is becoming increasingly popular because of the numerous health benefits of peptides.

What are peptides?

Peptides are an integral part of most biologic processes and are present throughout every cell and tissue in the body. Maintenance of appropriate concentration and activity levels of peptides is necessary to achieve homeostasis and maintain health. The function of a peptide is determined by its size and amino acid sequence.

All peptides are composed of amino acids chemically linked together. Peptides range in size from two amino acids–dipeptides–to 50 amino acids. Polypeptides consist of 50-100 aminoacids. Proteins are made of 100's to thousands of amino acids.

There are at least 700 different therapeutic peptides.

What are the different types of peptides?

Peptides can be:

Transporters- like glucose transporters that are necessary for glucose to travel from the blood into the muscle

Enzymes - are biological catalysts that speed up metabolic reactions. Most of the hundreds of enzymes are peptides.

Hormones- are biologic messengers that carry information from one tissue through the blood to a distant tissue. Two common classes of hormones are peptide and steroid hormones. Examples of peptide hormones include those involved in blood glucose regulation, such as insulin and glucagon, and those that regulate appetites, such as ghrelin and leptin.

Structural components - peptides like actin and myosin function as structural elements of the muscle and some other peptides contribute to bone shape and strength.

What are the most commonly Used Peptides?

1. Ipomorelin:

Ipamorelin is the first selective GHRP (growth hormone releasing peptide) secretagogue and ghrelin receptor agonist. Ipamorelin is one of the safest, most effective forms of growth hormone (GH) restoration, widely used to support age management, disease management, sports performance and GH deficiency treatment protocols, with virtually no side effects. It is considered “selective” since, unlike other GHRPs, this peptide doesn’t affect the release of cortisol, acetylcholine, prolactin or aldosterone, thereby minimizing side effects experienced with other GH therapies, such as increased hunger or irritability.

Because there are virtually no negative side effects, Ipamorelin can be prescribed more aggressively and more frequently than other therapies without the risk of elevated cortisol or acetylcholine blood plasma levels. This helps optimize HGH levels for a longer period of time, leading to more successful health outcomes. The physicians at Radiance recommend 8-12 week cycles depending on prior use and lifestyle factors.

Aging often comes with many undesirable effects on our bodies including increased fat, decreased muscle muscle mass and low energy. Some of these issues can be caused by adult growth hormone deficiency. Peptide therapies provide a healthy option to reinvigorate the natural release of growth hormone in the body and reverse the negative effects of aging.

The increased volume of GH produced by the pituitary gland causes an increase in the production of Insulin-Like Growth Factor-1 (IGF-1) by the liver and results in several health benefits such as:

Decreased body fat
Increased muscle mass
Increased strength
Improved energy
Improved quality of sleep
Improved sexual vitality
Increased physical and mental performance
Enhanced calcium retention
Improved bone density
Improved immune function
Improved skin elasticity and hair growth
Aids in connective tissue repair post injury

We chose to offer Ipamorelin as our preferred GHRP because of its selectivity, safety profile and efficacy. Others older peptides in the same class that you may have heard of are GHRP-6, GHRP-2, Hexamorelin, or Tesamorelin.

Dosing: Our glands have a saturation point, above which results in super-physiological changes that are not beneficial over time. We recommend staying under the saturation point with every dose, but more aggressive multiple day dosing can be tailored depending on your needs.

30 dose kit:

Includes-

Initial consult determining dosing and education of self-injection
Ipamorelin (vial of 30 doses)

Supplies: alcohol pads, insulin syringes, sharps container

Once punctured, each vial is best for 30 days, therefore, for more aggressive dosing like 2-3x/day dosing, you will need 2-3 vials for a 30-day period. We will determine the best dose for you based on your needs (anti-aging, fat loss, muscle growth, injury healing)

https://www.ncbi.nlm.nih.gov/pubmed/10496658

https://www.ncbi.nlm.nih.gov/pubmed/9849822

2. IPAMORELIN/CJC-1295

CJC-1295 is a growth hormone releasing hormone (GHRH) analog of 29 amino acids. CJC-1295 has been shown to increase human growth hormone (HGH) as well as insulin-like growth factor (IGF-1) secretion and has been able to do that in large amounts. CJC-1295 also works without increasing prolactin, leading to exponential fat loss and increased protein synthesis/muscle mass without negative side effects. CJC-1295 is shown to outperform Sermorelin (older peptide which is a GHRH as well) and is now surpassing its use, especially since the half life is longer.

From our special compounding pharmacies we are able to offer Ipamorelin/CJC-1295 combination peptide that is a combination of both a GHRH and a GHRP to act together on the pituitary and hypothalamus to exponentially increase levels of growth hormone in your body. Researchers have found the combination can increase GH over 5x than when either were administered alone. The combination allows for maximum release of GH because the CJC- 1295 and Ipamorelin have different mechanisms of actions and work on different receptors (GHRH-R and Ghrelin-R) which helps to:

Increase bone density
Strengthen the cardiovascular system
Increase muscle mass
Improve ability to burn fat
Increase sex drive
Improve recovery and repair from injuries
Regenerate nerve tissues
Strengthen the immune system
Improve cognition and memory
Outperforms sermorelin due to longer half-life and increased efficacy

We chose to offer this combination peptide again for its efficacy, safety profile and longer-life. The other GHRH analog that was widely used in the past that you may have heard of is Sermorelin,

These are normal physiological doses so miracles are not going to happen overnight, however, benefits are seen over time and within 6-8 weeks one will notice dramatic changes that aging masks including improved quality of sleep, improved recovery from workouts, mental clarity, improved skin elasticity and improved body composition. The healing is happening on a cellular level and will take time to notice, but it is amazing once you do!

30 dose kit:

Includes-

Initial consult determining dosing and education of self-injection
Ipamorelin/CJC-1295 (vial of 30 doses)

Supplies: alcohol pads, insulin syringes, sharps container

Retail cost $420

Ref:

https://www.ncbi.nlm.nih.gov/pubmed/16352683

https://www.ncbi.nlm.nih.gov/pubmed/16822960

https://www.ncbi.nlm.nih.gov/pubmed/11487592